Version 5.4
Homo sapiens Gene: LINGO1
Summary
InnateDB Gene IDBG-24364.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LINGO1
Gene Name leucine rich repeat and Ig domain containing 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000169783
Encoded Proteins
IDBP-24366
leucine rich repeat and Ig domain containing 1
IDBP-597054
leucine rich repeat and Ig domain containing 1
IDBP-599615
leucine rich repeat and Ig domain containing 1
IDBP-596908
leucine rich repeat and Ig domain containing 1
IDBP-747849
IDBP-746263
IDBP-747359
IDBP-746536
IDBP-746544
IDBP-746768
IDBP-745396
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 15:77613027-77820900
Strand Reverse strand
Band q24.3
Transcripts
ENST00000355300 ENSP00000347451
ENST00000561030 ENSP00000453853
ENST00000557798 ENSP00000453780
ENST00000559893 ENSP00000454051
ENST00000567605
ENST00000564472 ENSP00000454245
ENST00000566711 ENSP00000454687
ENST00000563316 ENSP00000457101
ENST00000564066
ENST00000562933 ENSP00000456516
ENST00000568951
ENST00000567726 ENSP00000454465
ENST00000561686 ENSP00000455605
ENST00000570216 ENSP00000454577
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
Biological Process
GO:0021954 central nervous system neuron development
GO:0031175 neuron projection development
GO:0043491 protein kinase B signaling
GO:0048011 neurotrophin TRK receptor signaling pathway
GO:0048715 negative regulation of oligodendrocyte differentiation
GO:0050770 regulation of axonogenesis
GO:0050771 negative regulation of axonogenesis
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000049556
View Gene Order
ENSBTAG00000023147
Not yet available
Pathways
NETPATH
REACTOME
REACT_13815
Axonal growth inhibition (RHOA activation) pathway
REACT_11061
Signalling by NGF pathway
REACT_13620
p75NTR regulates axonogenesis pathway
REACT_13776
p75 NTR receptor-mediated signalling pathway
REACT_111102
Signal Transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.603238 Hs.656765 Hs.743432
RefSeq NM_001301186 NM_001301187 NM_001301189 NM_001301191 NM_001301192 NM_001301194 NM_001301195 NM_001301197 NM_001301198 NM_001301199 NM_001301200 NM_032808 XM_006720723
HUGO
OMIM
CCDS CCDS45313 CCDS73766
HPRD 14322
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca