Homo sapiens Gene: GIMAP1
Summary
InnateDB Gene IDBG-244803.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GIMAP1
Gene Name GTPase, IMAP family member 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000213203
Encoded Proteins
GTPase, IMAP family member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene is thought to be involved in the differentiation of T helper (Th) cells of the Th1 lineage, and the related mouse gene has been shown to be critical for the development of mature B and T lymphocytes. Read-through transcription exists between this gene and the downstream GIMAP5 (GTPase, IMAP family member 5) gene. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:150716557-150724284
Strand Forward strand
Band q36.1
Transcripts
ENST00000307194 ENSP00000302833
ENST00000464461
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005525 GTP binding
Biological Process
GO:0030183 B cell differentiation
GO:0030217 T cell differentiation
Cellular Component
GO:0000139 Golgi membrane
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt Q8WWP7
TrEMBL
UniProt Splice Variant
Entrez Gene 170575
UniGene Hs.647079
RefSeq NM_130759
HUGO HGNC:23237
OMIM 608084
CCDS CCDS5906
HPRD
IMGT
EMBL AJ306287 AK091818 AK315127 BC040736 CH471173
GenPept AAH40736 BAC03754 BAG37580 CAC83740 EAW54095
RNA Seq Atlas 170575