Version 5.4
Homo sapiens Gene: CDKL2
Summary
InnateDB Gene IDBG-24650.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDKL2
Gene Name cyclin-dependent kinase-like 2 (CDC2-related kinase)
Synonyms KKIAMRE; P56
Species Homo sapiens
Ensembl Gene ENSG00000138769
Encoded Proteins
IDBP-24652
cyclin-dependent kinase-like 2 (CDC2-related kinase)
IDBP-371715
cyclin-dependent kinase-like 2 (CDC2-related kinase)
IDBP-475098
cyclin-dependent kinase-like 2 (CDC2-related kinase)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:75578005-75630716
Strand Reverse strand
Band q21.1
Transcripts
ENST00000307465 ENSP00000306340
ENST00000429927 ENSP00000412365
ENST00000515793
ENST00000506234 ENSP00000422666
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0007165 signal transduction
GO:0007548 sex differentiation
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029403
View Gene Order
ENSBTAG00000014038
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.591698
RefSeq NM_003948 XM_006714407
HUGO
OMIM
CCDS CCDS3570
HPRD 16021
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca