Version 5.4
Homo sapiens Gene: PLSCR3
Summary
InnateDB Gene IDBG-24786.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLSCR3
Gene Name phospholipid scramblase 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000187838
Encoded Proteins
IDBP-24788
phospholipid scramblase 3
IDBP-603288
phospholipid scramblase 3
IDBP-764093
IDBP-758359
IDBP-760361
IDBP-761689
IDBP-762177
IDBP-762900
IDBP-763602
IDBP-764720
IDBP-810214
TMEM256-PLSCR3 readthrough (NMD candidate)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:7389727-7394843
Strand Reverse strand
Band p13.1
Transcripts
ENST00000324822 ENSP00000316021
ENST00000535512 ENSP00000438547
ENST00000571541
ENST00000576362 ENSP00000460800
ENST00000575434 ENSP00000461843
ENST00000576201 ENSP00000459419
ENST00000573213 ENSP00000458988
ENST00000571078 ENSP00000458596
ENST00000573774
ENST00000571802 ENSP00000461205
ENST00000574401 ENSP00000459019
ENST00000573070 ENSP00000459122
ENST00000575543
ENST00000619711 ENSP00000483743
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0017124 SH3 domain binding
GO:0017128 phospholipid scramblase activity
GO:0048306 calcium-dependent protein binding
Biological Process
GO:0006915 apoptotic process
GO:0017121 phospholipid scrambling
GO:0042593 glucose homeostasis
GO:0042632 cholesterol homeostasis
GO:0071222 cellular response to lipopolysaccharide
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0031966 mitochondrial membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000019461
View Gene Order
ENSBTAG00000017747
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.534591
RefSeq NM_001201576 NM_020360
HUGO
OMIM
CCDS CCDS42253
HPRD 07400
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca