Version 5.4
Homo sapiens Gene: NAAA
Summary
InnateDB Gene IDBG-24959.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NAAA
Gene Name N-acylethanolamine acid amidase
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000138744
Encoded Proteins
IDBP-24961
N-acylethanolamine acid amidase
IDBP-483421
N-acylethanolamine acid amidase
IDBP-483606
N-acylethanolamine acid amidase
IDBP-483616
N-acylethanolamine acid amidase
IDBP-485415
N-acylethanolamine acid amidase
IDBP-811577
N-acylethanolamine acid amidase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an N-acylethanolamine-hydrolyzing enzyme which is highly similar to acid ceramidase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:75913657-75941051
Strand Reverse strand
Band q21.1
Transcripts
ENST00000286733 ENSP00000286733
ENST00000511606
ENST00000513045 ENSP00000423397
ENST00000507956 ENSP00000427641
ENST00000505594 ENSP00000426977
ENST00000507187 ENSP00000423142
ENST00000507940
ENST00000503636
ENST00000602782 ENSP00000473575
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008134 transcription factor binding
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
Biological Process
GO:0006629 lipid metabolic process
GO:0008150 biological_process
Cellular Component
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029413
View Gene Order
ENSBTAG00000019478
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.437365
RefSeq NM_014435 XM_005262920 XM_005262921 XM_005262925 XM_006714178 XM_006714180
HUGO
OMIM
CCDS CCDS43239
HPRD 12122
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca