Version 5.4
Homo sapiens Gene: DBF4
Summary
InnateDB Gene IDBG-25283.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DBF4
Gene Name DBF4 homolog (S. cerevisiae)
Synonyms ASK; CHIF; DBF4A; ZDBF1
Species Homo sapiens
Ensembl Gene ENSG00000006634
Encoded Proteins
IDBP-25285
DBF4 homolog (S. cerevisiae)
IDBP-381032
DBF4 homolog (S. cerevisiae)
IDBP-381045
DBF4 homolog (S. cerevisiae)
IDBP-381047
DBF4 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:87876216-87909541
Strand Forward strand
Band q21.12
Transcripts
ENST00000265728 ENSP00000265728
ENST00000413643 ENSP00000414083
ENST00000431138 ENSP00000407116
ENST00000430279 ENSP00000389397
ENST00000495067
ENST00000486925
ENST00000498144
ENST00000498726
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 26 [view]
Protein-Protein 24 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0008047 enzyme activator activity
GO:0008270 zinc ion binding
Biological Process
GO:0000082 G1/S transition of mitotic cell cycle
GO:0000278 mitotic cell cycle
GO:0006260 DNA replication
GO:0043085 positive regulation of catalytic activity
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000002297
View Gene Order
ENSBTAG00000014711
Not yet available
Pathways
NETPATH
REACTOME
REACT_6769
Activation of ATR in response to replication stress pathway
REACT_1095
Activation of the pre-replicative complex pathway
REACT_383
DNA Replication pathway
REACT_21267
Mitotic G1-G1/S phases pathway
REACT_828
G2/M Checkpoints pathway
REACT_734
DNA Replication Pre-Initiation pathway
REACT_1783
G1/S Transition pathway
REACT_115566
Cell Cycle pathway
REACT_1725
M/G1 Transition pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_1538
Cell Cycle Checkpoints pathway
KEGG
hsa04110
Cell cycle pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.485380 Hs.573845 Hs.701134
RefSeq NM_006716 XM_005250120 XM_005250121 XM_006715843
HUGO
OMIM
CCDS CCDS5611
HPRD 10371
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca