Version 5.4
Homo sapiens Gene: DLEC1
Summary
InnateDB Gene IDBG-25403.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DLEC1
Gene Name deleted in lung and esophageal cancer 1
Synonyms CFAP81; DLC1; F56
Species Homo sapiens
Ensembl Gene ENSG00000008226
Encoded Proteins
IDBP-25405
deleted in lung and esophageal cancer 1
IDBP-25407
deleted in lung and esophageal cancer 1
IDBP-371764
deleted in lung and esophageal cancer 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene contains 37 exons, spans approximately 59-kb, and is located in the 3p22-p21.3 chromosomal segment that is commonly deleted in various carcinomas. Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins. Aberrant transcription of this gene may be involved in carcinogenesis of the lung, esophagus, and kidney. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:38039205-38124025
Strand Forward strand
Band p22.2
Transcripts
ENST00000308059 ENSP00000308597
ENST00000346219 ENSP00000315914
ENST00000440294
ENST00000447130 ENSP00000404261
ENST00000469151
ENST00000477260
ENST00000478428
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008285 negative regulation of cell proliferation
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038060
View Gene Order
ENSBTAG00000008567
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.714499
RefSeq NM_007335 NM_007337 XM_005265630 XM_005265631 XM_006713439 XM_006713440 XM_006713441
HUGO
OMIM
CCDS CCDS2672
HPRD 07234
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca