Version 5.4
Mus musculus Gene: Gbp4
Summary
InnateDB Gene IDBG-255437.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gbp4
Gene Name guanylate binding protein 4
Synonyms AW228052; Mag-2; mKIAA4245; Mpa-2; Mpa2
Species Mus musculus
Ensembl Gene ENSMUSG00000079363
Encoded Proteins
IDBP-131218
guanylate binding protein 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:105115767-105139586
Strand Reverse strand
Band E5
Transcripts
ENSMUST00000100962 ENSMUSP00000098522
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001933 negative regulation of protein phosphorylation
GO:0006184 GTP catabolic process
GO:0031397 negative regulation of protein ubiquitination
GO:0032687 negative regulation of interferon-alpha production
GO:0042308 negative regulation of protein import into nucleus
GO:0050688 regulation of defense response to virus
GO:0071346 cellular response to interferon-gamma
Cellular Component
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL A4UUI3 B9EJ74
UniProt Splice Variant
Entrez Gene 17472
UniGene Mm.440525
RefSeq NM_001256005 NM_008620 XM_006534804 XM_006534805 XM_006534806
OMIM
CCDS CCDS57368
HPRD
IMGT
MGI ID MGI:97072
MGI Symbol Gbp4
EMBL AC123697 BC141364 BC147434 EF494423
GenPept AAI41365 AAI47435 ABO88216
RNA Seq Atlas 17472

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca