Version 5.4
Mus musculus Gene: Ube2v1
Summary
InnateDB Gene IDBG-262884.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ube2v1
Gene Name ubiquitin-conjugating enzyme E2 variant 1
Synonyms 0610011J09Rik; AI256840; CROC-1; CROC1; D7Bwg1382e; UEV-1
Species Mus musculus
Ensembl Gene ENSMUSG00000078923
Encoded Proteins
IDBP-213076
ubiquitin-conjugating enzyme E2 variant 1
IDBP-262886
ubiquitin-conjugating enzyme E2 variant 1
IDBP-540126
ubiquitin-conjugating enzyme E2 variant 1
IDBP-537368
ubiquitin-conjugating enzyme E2 variant 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:167607638-167632095
Strand Reverse strand
Band H3
Transcripts
ENSMUST00000060645 ENSMUSP00000053109
ENSMUST00000109207 ENSMUSP00000104830
ENSMUST00000151365 ENSMUSP00000114764
ENSMUST00000130284
ENSMUST00000144628
ENSMUST00000140216 ENSMUSP00000116578
ENSMUST00000144830
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0016881 acid-amino acid ligase activity
GO:0031624 ubiquitin conjugating enzyme binding
Biological Process
GO:0016567 protein ubiquitination
GO:0042275 error-free postreplication DNA repair
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0070534 protein K63-linked ubiquitination
Cellular Component
GO:0000151 ubiquitin ligase complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0031371 ubiquitin conjugating enzyme complex
GO:0035370 UBC13-UEV1A complex
GO:0043234 protein complex
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_229712
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation pathway
REACT_263004
Toll Like Receptor 2 (TLR2) Cascade pathway
REACT_239142
Innate Immune System pathway
REACT_225145
Downstream TCR signaling pathway
REACT_245896
MyD88 cascade initiated on plasma membrane pathway
REACT_205561
FCERI mediated NF-kB activation pathway
REACT_233584
Cytokine Signaling in Immune system pathway
REACT_255939
Toll Like Receptor TLR1:TLR2 Cascade pathway
REACT_230745
Immune System pathway
REACT_260773
Toll Like Receptor 5 (TLR5) Cascade pathway
REACT_254406
Toll Like Receptor TLR6:TLR2 Cascade pathway
REACT_198527
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling pathway
REACT_249409
Toll Like Receptor 9 (TLR9) Cascade pathway
REACT_188204
Fc epsilon receptor (FCERI) signaling pathway
REACT_251547
Toll-Like Receptors Cascades pathway
REACT_261687
Signaling by Interleukins pathway
REACT_211125
NOD1/2 Signaling Pathway pathway
REACT_256727
MyD88 dependent cascade initiated on endosome pathway
REACT_229531
Adaptive Immune System pathway
REACT_206758
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways pathway
REACT_262462
Activated TLR4 signalling pathway
REACT_224208
Interleukin-1 signaling pathway
REACT_242921
Toll Like Receptor 7/8 (TLR7/8) Cascade pathway
REACT_230045
MyD88:Mal cascade initiated on plasma membrane pathway
REACT_222648
TCR signaling pathway
REACT_198546
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation pathway
REACT_198543
IRAK1 recruits IKK complex pathway
REACT_261340
Toll Like Receptor 10 (TLR10) Cascade pathway
REACT_246719
Toll Like Receptor 4 (TLR4) Cascade pathway
KEGG
INOH
INOH website
CD4 T cell receptor signaling pathway
INOH website
IL-1 signaling pathway pathway
INOH website
Toll-like receptor signaling pathway pathway
INOH website
B cell receptor signaling pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.278783 Mm.360108 Mm.421998
RefSeq NM_023230 XM_006500013 XM_006500014 XM_006500015
OMIM
CCDS CCDS17103
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca