Version 5.4
Mus musculus Gene: Rad54b
Summary
InnateDB Gene IDBG-264821.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rad54b
Gene Name RAD54 homolog B (S. cerevisiae)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000078773
Encoded Proteins
IDBP-129600
RAD54 homolog B (S. cerevisiae)
IDBP-129602
RAD54 homolog B (S. cerevisiae)
IDBP-264823
RAD54 homolog B (S. cerevisiae)
IDBP-718357
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197275:
The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:11558922-11615805
Strand Forward strand
Band A1
Transcripts
ENSMUST00000070755 ENSMUSP00000066977
ENSMUST00000095145 ENSMUSP00000092767
ENSMUST00000108306 ENSMUSP00000103942
ENSMUST00000144499
ENSMUST00000178725 ENSMUSP00000136561
ENSMUST00000179731
ENSMUST00000179498
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0015616 DNA translocase activity
GO:0016787 hydrolase activity
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0006200 ATP catabolic process
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000197275
View Gene Order
ENSBTAG00000000632
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03440
Homologous recombination pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03440
Homologous recombination pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.249437 Mm.398659 Mm.399657
RefSeq NM_001039556 NM_001256145
OMIM
CCDS CCDS17970 CCDS57262
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca