InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rad54b

Summary

InnateDB Protein

IDBP-129600.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rad54b

Protein Name

RAD54 homolog B (S. cerevisiae)

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000066977

InnateDB Gene

IDBG-264821 (Rad54b)

Protein Structure

UniProt Annotation

Function

Involved in DNA repair and mitotic recombination. May play an active role in recombination processes in concert with other members of the RAD52 epistasis group. {ECO:0000269PubMed:12548566}.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.

Predicted by orthology
Total	22 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0004386	helicase activity
GO:0005524	ATP binding
GO:0015616	DNA translocase activity
GO:0016787	hydrolase activity

Biological Process

GO:0000724	double-strand break repair via homologous recombination
GO:0006200	ATP catabolic process

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:3605986

InterPro

IPR000330 SNF2-related
IPR001650 Helicase, C-terminal
IPR006935 Helicase/UvrB domain
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR021006 Histone deacetylase complex, subunit 2/3
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00176
PF00271
PF04851
PF11496

PRINTS

PIRSF

SMART

SM00490
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q6PFE3