Version 5.4
Homo sapiens Gene: KIDINS220
Summary
InnateDB Gene IDBG-27177.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KIDINS220
Gene Name kinase D-interacting substrate, 220kDa
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000134313
Encoded Proteins
IDBP-27179
kinase D-interacting substrate, 220kDa
IDBP-27181
kinase D-interacting substrate, 220kDa
IDBP-483640
kinase D-interacting substrate, 220kDa
IDBP-485344
kinase D-interacting substrate, 220kDa
IDBP-479434
kinase D-interacting substrate, 220kDa
IDBP-484115
kinase D-interacting substrate, 220kDa
IDBP-485343
kinase D-interacting substrate, 220kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:8725278-8837630
Strand Reverse strand
Band p25.1
Transcripts
ENST00000256707 ENSP00000256707
ENST00000319688 ENSP00000319947
ENST00000436566
ENST00000496383 ENSP00000420364
ENST00000473731 ENSP00000418974
ENST00000488729 ENSP00000417390
ENST00000489024 ENSP00000419964
ENST00000471685
ENST00000459813 ENSP00000419232
ENST00000474782
ENST00000471275
ENST00000496725
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030165 PDZ domain binding
Biological Process
GO:0000186 activation of MAPKK activity
GO:0001701 in utero embryonic development
GO:0010976 positive regulation of neuron projection development
GO:0016482 cytoplasmic transport
GO:0038180 nerve growth factor signaling pathway
GO:0048011 neurotrophin TRK receptor signaling pathway
GO:0048813 dendrite morphogenesis
GO:1990090 cellular response to nerve growth factor stimulus
Cellular Component
GO:0005770 late endosome
GO:0005829 cytosol
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0043234 protein complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036333
View Gene Order
ENSBTAG00000007963
Not yet available
Pathways
NETPATH
REACTOME
REACT_12002
ARMS-mediated activation pathway
REACT_11061
Signalling by NGF pathway
REACT_111102
Signal Transduction pathway
REACT_12058
Signalling to ERKs pathway
REACT_12056
NGF signalling via TRKA from the plasma membrane pathway
REACT_12005
Prolonged ERK activation events pathway
KEGG
hsa04722
Neurotrophin signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.9873
RefSeq NM_020738
HUGO
OMIM
CCDS CCDS42650
HPRD 17235
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca