Homo sapiens Gene: SLC14A2
Summary
InnateDB Gene IDBG-2796.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC14A2
Gene Name solute carrier family 14 (urea transporter), member 2
Synonyms hUT-A6; HUT2; UT-A2; UT2; UTA; UTR
Species Homo sapiens
Ensembl Gene ENSG00000132874
Encoded Proteins
solute carrier family 14 (urea transporter), member 2
solute carrier family 14 (urea transporter), member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene belongs to the urea transporter family. In mammalian cells, urea is the chief end product of nitrogen catabolism, and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney, and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:45212995-45683686
Strand Forward strand
Band q12.3
Transcripts
ENST00000255226 ENSP00000255226
ENST00000323329 ENSP00000320689
ENST00000586448 ENSP00000465953
ENST00000589658 ENSP00000465349
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015204 urea transmembrane transporter activity
GO:0050839 cell adhesion molecule binding
Biological Process
GO:0015840 urea transport
GO:0055085 transmembrane transport
GO:0071918 urea transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
Transmembrane transport of small molecules pathway
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E7EPU1
UniProt Splice Variant
Entrez Gene 8170
UniGene Hs.710927
RefSeq NM_001242692 NM_007163 XM_005276012
HUGO HGNC:10919
OMIM 601611
CCDS CCDS11924
HPRD 03366
IMGT
EMBL AC021517 AC021810 AC023421 AC090376 AC091151
GenPept
RNA Seq Atlas 101930602 8170