Version 5.4
Homo sapiens Gene: GRHL1
Summary
InnateDB Gene IDBG-28061.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GRHL1
Gene Name grainyhead-like 1 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000134317
Encoded Proteins
IDBP-28063
grainyhead-like 1 (Drosophila)
IDBP-292747
grainyhead-like 1 (Drosophila)
IDBP-363229
grainyhead-like 1 (Drosophila)
IDBP-477291
grainyhead-like 1 (Drosophila)
IDBP-475203
grainyhead-like 1 (Drosophila)
IDBP-484886
grainyhead-like 1 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the grainyhead family of transcription factors. The encoded protein can exist as a homodimer or can form heterodimers with sister-of-mammalian grainyhead or brother-of-mammalian grainyhead. This protein functions as a transcription factor during development. [provided by RefSeq, Jun 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:9951693-10002277
Strand Forward strand
Band p25.1
Transcripts
ENST00000324907 ENSP00000324693
ENST00000405379 ENSP00000384209
ENST00000439493 ENSP00000387521
ENST00000497403
ENST00000464418 ENSP00000420654
ENST00000472167 ENSP00000418275
ENST00000494520
ENST00000480736 ENSP00000419831
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organismal development
GO:0044255 cellular lipid metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020656
View Gene Order
ENSBTAG00000007485
Not yet available
Pathways
NETPATH
REACTOME
REACT_116145
PPARA activates gene expression pathway
REACT_19241
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
REACT_22279
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9NZI5
TrEMBL F8WFB0
UniProt Splice Variant
Entrez Gene 29841
UniGene Hs.418493
RefSeq NM_198182
HUGO HGNC:17923
OMIM 609786
CCDS CCDS33144
HPRD 18176
IMGT
EMBL AC010969 AF198489 AF411210 AK312950 BC067519 BC067520 BC067521 CH471053
GenPept AAF32276 AAH67519 AAH67520 AAH67521 AAM22616 AAX93273 BAG35791 EAX00973
RNA Seq Atlas 29841

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca