InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: TRIM16

Summary

InnateDB Gene

IDBG-281555.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TRIM16

Gene Name

tripartite motif containing 16

Synonyms

EBBP

Species

Homo sapiens

Ensembl Gene

ENSG00000221926

Encoded Proteins

IDBP-31695

tripartite motif containing 16

IDBP-369611

tripartite motif containing 16

IDBP-758413

IDBP-757738

IDBP-759938

IDBP-761428

IDBP-760703

IDBP-762492

IDBP-761117

IDBP-762936

IDBP-764442

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene was identified as an estrogen and anti-estrogen regulated gene in epithelial cells stably expressing estrogen receptor. The protein encoded by this gene contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family. The proteins of this family have been reported to be involved in a variety of biological processes including cell growth, differentiation and pathogenesis. Expression of this gene was detected in most tissues. Its function, however, has not yet been determined. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 17:15627960-15684311

Strand

Reverse strand

Band

p12

Transcripts

ENST00000336708	ENSP00000338989
ENST00000416464	ENSP00000399918
ENST00000473368
ENST00000473540
ENST00000460728
ENST00000473659
ENST00000494759	ENSP00000465169
ENST00000577326
ENST00000581224
ENST00000577886	ENSP00000462903
ENST00000582708
ENST00000579219	ENSP00000463639
ENST00000579630
ENST00000578237	ENSP00000463188
ENST00000580388
ENST00000578744	ENSP00000465907
ENST00000582182
ENST00000579843
ENST00000577446	ENSP00000467031
ENST00000577372	ENSP00000463293
ENST00000580110	ENSP00000464072
ENST00000581200	ENSP00000463360
ENST00000584142
ENST00000579535
ENST00000579272

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.

Experimentally validated
Total	11 [view]
Protein-Protein	11 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0019966	interleukin-1 binding
GO:0032089	NACHT domain binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0032526	response to retinoic acid
GO:0043966	histone H3 acetylation
GO:0043967	histone H4 acetylation
GO:0045618	positive regulation of keratinocyte differentiation
GO:0045893	positive regulation of transcription, DNA-templated
GO:0046683	response to organophosphorus
GO:0048386	positive regulation of retinoic acid receptor signaling pathway
GO:0050718	positive regulation of interleukin-1 beta secretion
GO:0060416	response to growth hormone

Cellular Component

GO:0005622	intracellular
GO:0005737	cytoplasm
GO:0016605	PML body

Orthologs

Species

Mus musculus

Gene ID

Gene Order

ENSMUSG00000047821

View Gene Order

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Hs.638613 Hs.735748

RefSeq

NM_006470

HUGO

OMIM

CCDS

CCDS11171

HPRD

15552

IMGT

EMBL

GenPept

RNA Seq Atlas