Homo sapiens Gene: AEN
Summary
InnateDB Gene IDBG-28670.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AEN
Gene Name apoptosis enhancing nuclease
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000181026
Encoded Proteins
apoptosis enhancing nuclease
apoptosis enhancing nuclease
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 15:88621296-88632282
Strand Forward strand
Band q26.1
Transcripts
ENST00000332810 ENSP00000331944
ENST00000557787
ENST00000559528 ENSP00000453631
ENST00000560174
ENST00000558327
ENST00000557927
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0004527 exonuclease activity
Biological Process
GO:0010212 response to ionizing radiation
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0031965 nuclear membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
p73 transcription factor network
Validated transcriptional targets of TAp63 isoforms
Cross-References
SwissProt Q8WTP8
TrEMBL H0YMJ6 Q8WYW8
UniProt Splice Variant
Entrez Gene 64782
UniGene Hs.436102
RefSeq NM_022767 XM_005254966 XM_005254967 XM_006720644
HUGO HGNC:25722
OMIM 610177
CCDS CCDS10344
HPRD 08573
IMGT
EMBL AC013489 AF318330 AF327352 AK022546 BC005164 BC014407 BC020988 CH471101
GenPept AAH05164 AAH14407 AAH20988 AAL55837 AAL56012 BAB14091 EAX02009
RNA Seq Atlas 64782