Version 5.4
Homo sapiens Protein: AEN
Summary
InnateDB Protein IDBP-604136.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AEN
Protein Name apoptosis enhancing nuclease
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000453631
InnateDB Gene IDBG-28670 (AEN)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID
InterPro IPR012337 Ribonuclease H-like domain
IPR013520 Exonuclease, RNase T/DNA polymerase III
PFAM PF00929
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H0YMJ6
UniProt Splice Variant
Entrez Gene 64782
UniGene Hs.436102
RefSeq
HUGO HGNC:25722
OMIM 610177
CCDS
HPRD 08573
IMGT
EMBL AC013489
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca