Version 5.4
Homo sapiens Gene: CPQ
Summary
InnateDB Gene IDBG-29540.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CPQ
Gene Name carboxypeptidase Q
Synonyms LDP; PGCP
Species Homo sapiens
Ensembl Gene ENSG00000104324
Encoded Proteins
IDBP-29542
Plasma glutamate carboxypeptidase
IDBP-485056
Plasma glutamate carboxypeptidase
IDBP-482800
Plasma glutamate carboxypeptidase
IDBP-484384
Plasma glutamate carboxypeptidase
IDBP-481925
Plasma glutamate carboxypeptidase
IDBP-476832
Plasma glutamate carboxypeptidase
IDBP-808752
carboxypeptidase Q
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a metallopeptidase that belongs to the peptidase M28 family. The encoded protein may catalyze the cleavage of dipeptides with unsubstituted terminals into amino acids. [provided by RefSeq, Jul 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:96645227-97149654
Strand Forward strand
Band q22.1
Transcripts
ENST00000220763 ENSP00000220763
ENST00000519900 ENSP00000431024
ENST00000517742 ENSP00000429146
ENST00000519484 ENSP00000431114
ENST00000521142 ENSP00000429934
ENST00000522617 ENSP00000429134
ENST00000525310
ENST00000532528
ENST00000529551
ENST00000621294 ENSP00000482198
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004180 carboxypeptidase activity
GO:0016787 hydrolase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0070573 metallodipeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0006590 thyroid hormone generation
GO:0008152 metabolic process
GO:0042246 tissue regeneration
GO:0043171 peptide catabolic process
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000039007
View Gene Order
ENSBTAG00000011908
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_016134 XM_005250755
HUGO
OMIM
CCDS CCDS6273
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca