Version 5.4
Homo sapiens Gene: AP3S2
Summary
InnateDB Gene IDBG-29690.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AP3S2
Gene Name adaptor-related protein complex 3, sigma 2 subunit
Synonyms AP3S3; sigma3b
Species Homo sapiens
Ensembl Gene ENSG00000157823
Encoded Proteins
IDBP-29692
adaptor-related protein complex 3, sigma 2 subunit
IDBP-380245
adaptor-related protein complex 3, sigma 2 subunit
IDBP-598148
adaptor-related protein complex 3, sigma 2 subunit
IDBP-594684
adaptor-related protein complex 3, sigma 2 subunit
IDBP-592446
adaptor-related protein complex 3, sigma 2 subunit
IDBP-592727
adaptor-related protein complex 3, sigma 2 subunit
IDBP-589876
adaptor-related protein complex 3, sigma 2 subunit
IDBP-807722
adaptor-related protein complex 3, sigma 2 subunit
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This locus represents naturally occurring read-through transcription between the neighboring C15orf38 (chromosome 15 open reading frame 38) and AP3S2 (adaptor-related protein complex 3, sigma 2 subunit) genes. The read-through transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:89830599-89894638
Strand Reverse strand
Band q26.1
Transcripts
ENST00000336418 ENSP00000338777
ENST00000423566 ENSP00000394170
ENST00000558926
ENST00000558011 ENSP00000453223
ENST00000557999 ENSP00000452862
ENST00000558806 ENSP00000454027
ENST00000559162
ENST00000558999 ENSP00000453380
ENST00000558186
ENST00000560184
ENST00000560251 ENSP00000453288
ENST00000559601
ENST00000617003 ENSP00000481434
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008565 protein transporter activity
Biological Process
GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0008089 anterograde axon cargo transport
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
GO:0048490 anterograde synaptic vesicle transport
Cellular Component
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0030117 membrane coat
GO:0030123 AP-3 adaptor complex
GO:0030659 cytoplasmic vesicle membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
hsa04142
Lysosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 10239
UniGene
RefSeq NM_005829
HUGO HGNC:571
OMIM 602416
CCDS CCDS10357
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 100526783 10239

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca