Homo sapiens Gene: ST8SIA5
Summary
InnateDB Gene IDBG-2995.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ST8SIA5
Gene Name ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000101638
Encoded Proteins
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a type II membrane protein that may be present in the Golgi apparatus. The encoded protein, which is a member of glycosyltransferase family 29, may be involved in the synthesis of gangliosides GD1c, GT1a, GQ1b, and GT3 from GD1a, GT1b, GM1b, and GD3, respectively. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:46667821-46759257
Strand Reverse strand
Band q21.1
Transcripts
ENST00000315087 ENSP00000321343
ENST00000538168 ENSP00000445492
ENST00000536490 ENSP00000443683
ENST00000590488 ENSP00000466787
ENST00000591375 ENSP00000468112
ENST00000588155
ENST00000587428
ENST00000589088
ENST00000590497
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity
GO:0008373 sialyltransferase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006486 protein glycosylation
GO:0006688 glycosphingolipid biosynthetic process
GO:0097503 sialylation
Cellular Component
GO:0030173 integral component of Golgi membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Asparagine N-linked glycosylation pathway
Post-translational protein modification pathway
Synthesis of substrates in N-glycan biosythesis pathway
Sialic acid metabolism pathway
Metabolism of proteins pathway
KEGG
Glycosphingolipid biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.465025 Hs.733140
RefSeq NM_013305 XM_005258250 XM_006722443 XM_006722444
HUGO
OMIM
CCDS CCDS11930
HPRD 06199
IMGT
EMBL
GenPept
RNA Seq Atlas