Version 5.4
Homo sapiens Gene: YY2
Summary
InnateDB Gene IDBG-299569.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol YY2
Gene Name YY2 transcription factor
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000230797
Encoded Proteins
IDBP-365218
YY2 transcription factor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a transcription factor that includes several Kruppel-like zinc fingers in its C-terminal region. It possesses both activation and repression domains, and it can therefore have both positive and negative effects on the transcription of target genes. This gene has an intronless coding region, and it appears to have arisen by retrotransposition of the related YY1 transcription factor gene, which is located on chromosome 14. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:21855987-21858727
Strand Forward strand
Band p22.12
Transcripts
ENST00000429584 ENSP00000389381
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Orthologs
No orthologs found for this gene
Cross-References
SwissProt O15391
TrEMBL
UniProt Splice Variant
Entrez Gene 404281
UniGene Hs.673601
RefSeq NM_206923
HUGO HGNC:31684
OMIM 300570
CCDS CCDS14202
HPRD
IMGT
EMBL AK091850 AY567472 BC137215 BC137217 CH471074 U73479
GenPept AAD08633 AAI37216 AAI37218 AAS68634 BAG52427 EAW98983
RNA Seq Atlas 404281

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca