Version 5.4
Homo sapiens Protein: YY2
Summary
InnateDB Protein IDBP-365218.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol YY2
Protein Name YY2 transcription factor
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000389381
InnateDB Gene IDBG-299569 (YY2)
Protein Structure
UniProt Annotation
Function Functions as a multifunctional transcription factor that may exhibit positive and negative control on a large number of genes. May antagonize YY1 and function in development and differentiation. {ECO:0000269PubMed:16260628}.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in kidney, liver, spleen and testis but not in colon. {ECO:0000269PubMed:15087442}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
IPR017114 Transcription factor yin/yang
PFAM PF00096
PRINTS
PIRSF PIRSF037113
SMART SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O15391
PhosphoSite PhosphoSite-O15391
TrEMBL
UniProt Splice Variant
Entrez Gene 404281
UniGene Hs.673601
RefSeq NP_996806
HUGO HGNC:31684
OMIM 300570
CCDS CCDS14202
HPRD 15684
IMGT
EMBL AK091850 AY567472 BC137215 BC137217 CH471074 U73479
GenPept AAD08633 AAI37216 AAI37218 AAS68634 BAG52427 EAW98983

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca