Version 5.4
Homo sapiens Gene: MYO18B
Summary
InnateDB Gene IDBG-3049.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MYO18B
Gene Name myosin XVIIIB
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000133454
Encoded Proteins
IDBP-3051
myosin XVIIIB
IDBP-294906
myosin XVIIIB
IDBP-590361
myosin XVIIIB
IDBP-596033
myosin XVIIIB
IDBP-586628
myosin XVIIIB
IDBP-598691
myosin XVIIIB
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene may regulate muscle-specific genes when in the nucleus and may influence intracellular trafficking when in the cytoplasm. The encoded protein functions as a homodimer and may interact with F actin. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:25742144-26031041
Strand Forward strand
Band q12.1
Transcripts
ENST00000335473 ENSP00000334563
ENST00000407587 ENSP00000386096
ENST00000418374
ENST00000536101 ENSP00000441229
ENST00000539302 ENSP00000437587
ENST00000534908
ENST00000536204
ENST00000539544
ENST00000543971 ENSP00000444262
ENST00000540454 ENSP00000441301
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003774 motor activity
GO:0003779 actin binding
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0001570 vasculogenesis
GO:0001701 in utero embryonic development
GO:0006412 translation
GO:0008152 metabolic process
GO:0048739 cardiac muscle fiber development
Cellular Component
GO:0005634 nucleus
GO:0016459 myosin complex
GO:0016461 unconventional myosin complex
GO:0030017 sarcomere
GO:0030018 Z disc
GO:0031941 filamentous actin
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000072720
View Gene Order
ENSBTAG00000000698
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.417959 Hs.691493
RefSeq NM_032608 XM_005261786 XM_005261787 XM_005261788 XM_006724340 XM_006724341
HUGO
OMIM
CCDS CCDS54507
HPRD 09529
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca