Homo sapiens Gene: UNC45A
Summary
InnateDB Gene IDBG-30609.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UNC45A
Gene Name unc-45 homolog A (C. elegans)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000140553
Encoded Proteins
unc-45 homolog A (C. elegans)
unc-45 homolog A (C. elegans)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary UNC45A plays a role in cell proliferation and myoblast fusion, binds progesterone receptor (PGR; MIM 607311) and HSP90 (HSPCA; MIM 140571), and acts as a regulator of the progesterone receptor chaperoning pathway (Price et al., 2002 [PubMed 12356907]; Chadli et al., 2006 [PubMed 16478993]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:90930180-90954093
Strand Forward strand
Band q26.1
Transcripts
ENST00000394275 ENSP00000377816
ENST00000418476 ENSP00000407487
ENST00000480470
ENST00000461266
ENST00000497152
ENST00000495068
ENST00000486253
ENST00000487875
ENST00000471780
ENST00000556319
ENST00000553671
ENST00000557212
ENST00000556482
ENST00000556704
ENST00000554481
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.
Experimentally validated
Total 31 [view]
Protein-Protein 31 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0051879 Hsp90 protein binding
Biological Process
GO:0007517 muscle organ development
GO:0030154 cell differentiation
GO:0061077 chaperone-mediated protein folding
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.389461 Hs.690345
RefSeq NM_001039675 NM_018671 XM_005254963
HUGO
OMIM
CCDS CCDS10367 CCDS42082
HPRD 18070
IMGT
EMBL
GenPept
RNA Seq Atlas