Version 5.4
Homo sapiens Gene: ARHGAP44
Summary
InnateDB Gene IDBG-31150.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARHGAP44
Gene Name Rho GTPase activating protein 44
Synonyms NPC-A-10; RICH2
Species Homo sapiens
Ensembl Gene ENSG00000006740
Encoded Proteins
IDBP-31152
Rho GTPase activating protein 44
IDBP-31154
Rho GTPase activating protein 44
IDBP-31156
Rho GTPase activating protein 44
IDBP-584860
Rho GTPase activating protein 44
IDBP-761691
IDBP-762601
IDBP-764145
IDBP-810737
Rho GTPase activating protein 44
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:12789539-12991643
Strand Forward strand
Band p12
Transcripts
ENST00000262444 ENSP00000262444
ENST00000340825 ENSP00000342566
ENST00000379672 ENSP00000368994
ENST00000538915
ENST00000544416 ENSP00000437542
ENST00000578442
ENST00000578087
ENST00000583608 ENSP00000463905
ENST00000581437 ENSP00000465509
ENST00000584974
ENST00000580768 ENSP00000462141
ENST00000616670 ENSP00000482851
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0005515 protein binding
GO:0005543 phospholipid binding
Biological Process
GO:0006887 exocytosis
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0043547 positive regulation of GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0030054 cell junction
GO:0031256 leading edge membrane
GO:0043197 dendritic spine
GO:0045202 synapse
GO:0055037 recycling endosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000033389
View Gene Order
ENSBTAG00000021938
Not yet available
Pathways
NETPATH
REACTOME
REACT_11051
Rho GTPase cycle pathway
REACT_11044
Signaling by Rho GTPases pathway
REACT_111102
Signal Transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.499758 Hs.618923 Hs.667038 Hs.737991 Hs.740175
RefSeq NM_014859 XM_005256888
HUGO
OMIM
CCDS CCDS45616
HPRD 13810
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca