Homo sapiens Gene: FBXO24
Summary
InnateDB Gene IDBG-31497.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBXO24
Gene Name F-box protein 24
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000106336
Encoded Proteins
F-box protein 24
F-box protein 24
F-box protein 24
F-box protein 24
F-box protein 24
F-box protein 24
F-box protein 24
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:100583982-100601117
Strand Forward strand
Band q22.1
Transcripts
ENST00000241071 ENSP00000241071
ENST00000427939 ENSP00000416558
ENST00000461079 ENSP00000419587
ENST00000498195
ENST00000488079 ENSP00000418814
ENST00000474649
ENST00000465843 ENSP00000419602
ENST00000466053 ENSP00000417179
ENST00000468962 ENSP00000420239
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 15 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
GO:0000151 ubiquitin ligase complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt O75426
TrEMBL
UniProt Splice Variant
Entrez Gene 26261
UniGene Hs.283764
RefSeq NM_012172 NM_001163499 NM_033506
HUGO HGNC:13595
OMIM 609097
CCDS CCDS5699 CCDS55138 CCDS5698
HPRD 16438
IMGT
EMBL AC069281 AF053356 AF174604 AK301864 AK302252 AL136811 BC067293 CH236956 CH471091
GenPept AAC78801 AAF04525 AAH67293 AAP21862 AAP21863 BAG63303 BAG63604 CAB66745 EAL23827 EAW76517
RNA Seq Atlas 26261