Version 5.4
Mus musculus Gene: Fbxo24
Summary
InnateDB Gene IDBG-488112.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fbxo24
Gene Name F-box protein 24
Synonyms 4933422D21Rik; Fbx24
Species Mus musculus
Ensembl Gene ENSMUSG00000089984
Encoded Proteins
IDBP-205263
F-box protein 24
IDBP-259058
F-box protein 24
IDBP-535014
F-box protein 24
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000106336:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:137612503-137629002
Strand Reverse strand
Band G2
Transcripts
ENSMUST00000031732 ENSMUSP00000031732
ENSMUST00000111002 ENSMUSP00000106630
ENSMUST00000136028 ENSMUSP00000121077
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000106336
View Gene Order
ENSBTAG00000003169
Not yet available
Cross-References
SwissProt
TrEMBL D3YZY9
UniProt Splice Variant
Entrez Gene 71176
UniGene Mm.474695
RefSeq NM_027708 XM_006504617 XM_006504619
OMIM
CCDS CCDS51674
HPRD
IMGT
MGI ID MGI:1918426
MGI Symbol Fbxo24
EMBL AC124730
GenPept
RNA Seq Atlas 71176

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca