Version 5.4
Homo sapiens Gene: NUDT15
Summary
InnateDB Gene IDBG-31578.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NUDT15
Gene Name nudix (nucleoside diphosphate linked moiety X)-type motif 15
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000136159
Encoded Proteins
IDBP-31580
nudix (nucleoside diphosphate linked moiety X)-type motif 15
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 13:48037567-48047222
Strand Forward strand
Band q14.2
Transcripts
ENST00000258662 ENSP00000258662
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
GO:0016787 hydrolase activity
GO:0035539 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006203 dGTP catabolic process
GO:0034656 nucleobase-containing small molecule catabolic process
GO:0044281 small molecule metabolic process
GO:0055086 nucleobase-containing small molecule metabolic process
Cellular Component
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000033405
View Gene Order
ENSBTAG00000019501
Not yet available
Pathways
NETPATH
REACTOME
REACT_150237
Phosphate bond hydrolysis by NUDT proteins pathway
REACT_1698
Metabolism of nucleotides pathway
REACT_111217
Metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9NV35
TrEMBL
UniProt Splice Variant
Entrez Gene 55270
UniGene Hs.144407
RefSeq NM_018283
HUGO HGNC:23063
OMIM 615792
CCDS CCDS9407
HPRD
IMGT
EMBL AK001818 AL158196 BC064607 BC107875 BC133015 BC133017 CH471075
GenPept AAH64607 AAI07876 AAI33016 AAI33018 BAA91925 CAI17017 EAX08782
RNA Seq Atlas 55270

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca