Version 5.4
Homo sapiens Gene: MRI1
Summary
InnateDB Gene IDBG-32307.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MRI1
Gene Name methylthioribose-1-phosphate isomerase homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000037757
Encoded Proteins
IDBP-32309
methylthioribose-1-phosphate isomerase homolog (S. cerevisiae)
IDBP-32311
methylthioribose-1-phosphate isomerase homolog (S. cerevisiae)
IDBP-764768
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:13764532-13774282
Strand Forward strand
Band p13.13
Transcripts
ENST00000040663 ENSP00000040663
ENST00000319545 ENSP00000314871
ENST00000589290
ENST00000588526
ENST00000593245 ENSP00000466369
ENST00000591688
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0042802 identical protein binding
GO:0046523 S-methyl-5-thioribose-1-phosphate isomerase activity
Biological Process
GO:0000096 sulfur amino acid metabolic process
GO:0006595 polyamine metabolic process
GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine
GO:0019509 L-methionine biosynthetic process from methylthioadenosine
GO:0034641 cellular nitrogen compound metabolic process
GO:0044237 cellular metabolic process
GO:0044249 cellular biosynthetic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0042995 cell projection
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000004996
View Gene Order
ENSBTAG00000002524
Not yet available
Pathways
NETPATH
REACTOME
REACT_75881
Methionine salvage pathway pathway
REACT_14820
Metabolism of polyamines pathway
REACT_115639
Sulfur amino acid metabolism pathway
REACT_13
Metabolism of amino acids and derivatives pathway
REACT_111217
Metabolism pathway
KEGG
hsa00270
Cysteine and methionine metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q9BV20
TrEMBL K7EM59
UniProt Splice Variant
Entrez Gene 84245
UniGene Hs.712891
RefSeq NM_001031727 NM_032285
HUGO HGNC:28469
OMIM 615105
CCDS CCDS12297 CCDS32923
HPRD
IMGT
EMBL AC008686 AL834276 AY358176 BC001703 CH471106
GenPept AAH01703 AAQ88543 CAD38951 EAW84370 EAW84371
RNA Seq Atlas 84245

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca