Version 5.4
Homo sapiens Gene: CERS5
Summary
InnateDB Gene IDBG-32436.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CERS5
Gene Name ceramide synthase 5
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000139624
Encoded Proteins
IDBP-32438
ceramide synthase 5
IDBP-32440
ceramide synthase 5
IDBP-374803
ceramide synthase 5
IDBP-374805
ceramide synthase 5
IDBP-598407
ceramide synthase 5
IDBP-583610
ceramide synthase 5
IDBP-601633
ceramide synthase 5
IDBP-593133
ceramide synthase 5
IDBP-585800
ceramide synthase 5
IDBP-583791
ceramide synthase 5
IDBP-595876
ceramide synthase 5
IDBP-588305
ceramide synthase 5
IDBP-590366
ceramide synthase 5
IDBP-600319
ceramide synthase 5
IDBP-588140
ceramide synthase 5
IDBP-585065
ceramide synthase 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:50129306-50167533
Strand Reverse strand
Band q13.12
Transcripts
ENST00000317551 ENSP00000325485
ENST00000380189 ENSP00000369536
ENST00000438450 ENSP00000407896
ENST00000422340 ENSP00000389050
ENST00000551697 ENSP00000448794
ENST00000551005
ENST00000547787 ENSP00000447410
ENST00000546406
ENST00000550919 ENSP00000449311
ENST00000553122 ENSP00000447266
ENST00000550079
ENST00000551757
ENST00000548942
ENST00000550547 ENSP00000447029
ENST00000547138
ENST00000546676
ENST00000542320 ENSP00000442918
ENST00000547800 ENSP00000448295
ENST00000549089
ENST00000548930
ENST00000551384
ENST00000549389 ENSP00000448755
ENST00000550258 ENSP00000446937
ENST00000547455 ENSP00000448257
ENST00000546514 ENSP00000446931
ENST00000549942
ENST00000550899 ENSP00000450072
ENST00000547852
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0050291 sphingosine N-acyltransferase activity
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006665 sphingolipid metabolic process
GO:0030148 sphingolipid biosynthetic process
GO:0044281 small molecule metabolic process
GO:0046513 ceramide biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
GO:0031965 nuclear membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000023021
View Gene Order
ENSBTAG00000017395
Not yet available
Pathways
NETPATH
REACTOME
REACT_115810
Sphingolipid de novo biosynthesis pathway
REACT_19323
Sphingolipid metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
KEGG
hsa00600
Sphingolipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 91012
UniGene Hs.270525 Hs.672010 Hs.685523 Hs.694201
RefSeq NM_001281731 NM_147190
HUGO HGNC:23749
OMIM 615335
CCDS CCDS61120 CCDS8801
HPRD 13963
IMGT
EMBL
GenPept
RNA Seq Atlas 91012

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca