Version 5.4
Homo sapiens Gene: DIP2B
Summary
InnateDB Gene IDBG-32709.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DIP2B
Gene Name DIP2 disco-interacting protein 2 homolog B (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000066084
Encoded Proteins
IDBP-32711
DIP2 disco-interacting protein 2 homolog B (Drosophila)
IDBP-584987
DIP2 disco-interacting protein 2 homolog B (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the disco-interacting protein homolog 2 protein family. The encoded protein contains a binding site for the transcriptional regulator DNA methyltransferase 1 associated protein 1 as well as AMP-binding sites. The presence of these sites suggests that the encoded protein may participate in DNA methylation. This gene is located near a folate-sensitive fragile site, and CGG-repeat expansion in the promoter of this gene which affects transcription has been detected in individuals containing this fragile site on chromosome 12. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:50504985-50748667
Strand Forward strand
Band q13.12
Transcripts
ENST00000301180 ENSP00000301180
ENST00000549620
ENST00000546719
ENST00000552328
ENST00000546732 ENSP00000450181
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0008134 transcription factor binding
Biological Process
GO:0008150 biological_process
GO:0008152 metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000023026
View Gene Order
ENSBTAG00000005246
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 57609
UniGene Hs.505516 Hs.614140 Hs.630630
RefSeq NM_173602 XM_005269044 XM_006719520 XM_006719521 XM_006719522
HUGO HGNC:29284
OMIM 611379
CCDS CCDS31799
HPRD 11148
IMGT
EMBL
GenPept
RNA Seq Atlas 57609

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca