Version 5.4
Homo sapiens Protein: DIP2B
Summary
InnateDB Protein IDBP-32711.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DIP2B
Protein Name DIP2 disco-interacting protein 2 homolog B (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000301180
InnateDB Gene IDBG-32709 (DIP2B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity Moderately expressed in adult brain, placenta, skeletal muscle, heart, kidney, pancreas, lung, spleen and colon. Expression was weaker in adult liver, kidney, spleen, and ovary, and in fetal brain and liver. In the brain, it is expressed in the cerebral cortex; the frontal, parietal, occipital and temporal lobes; the paracentral gyrus; the pons; the corpus callosum and the hippocampus. Highest expression levels in the brain were found in the cerebral cortex and the frontal and parietal lobes. {ECO:0000269PubMed:10819331, ECO:0000269PubMed:17236128}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0008134 transcription factor binding
Biological Process
GO:0008150 biological_process
GO:0008152 metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000873 AMP-dependent synthetase/ligase
IPR010506 DMAP1-binding
PFAM PF00501
PF06464
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9P265
PhosphoSite PhosphoSite-Q9P265
TrEMBL Q96IB4
UniProt Splice Variant
Entrez Gene 57609
UniGene Hs.630630
RefSeq NP_775873
HUGO HGNC:29284
OMIM 611379
CCDS CCDS31799
HPRD 11148
IMGT
EMBL AB040896 AC078818 AC090058 AK091597 AK097369 BC007671 BC030156 BC075027 CH471111
GenPept AAH07671 AAH30156 AAH75027 BAA95987 BAC03705 BAC05025 EAW58149

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca