Version 5.4
Homo sapiens Gene: SYBU
Summary
InnateDB Gene IDBG-32815.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYBU
Gene Name syntabulin (syntaxin-interacting)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000147642
Encoded Proteins
IDBP-32817
syntabulin (syntaxin-interacting)
IDBP-231552
syntabulin (syntaxin-interacting)
IDBP-295521
syntabulin (syntaxin-interacting)
IDBP-295518
syntabulin (syntaxin-interacting)
IDBP-375172
syntabulin (syntaxin-interacting)
IDBP-375177
syntabulin (syntaxin-interacting)
IDBP-375178
syntabulin (syntaxin-interacting)
IDBP-375179
syntabulin (syntaxin-interacting)
IDBP-375181
syntabulin (syntaxin-interacting)
IDBP-599301
syntabulin (syntaxin-interacting)
IDBP-590569
syntabulin (syntaxin-interacting)
IDBP-602971
syntabulin (syntaxin-interacting)
IDBP-596393
syntabulin (syntaxin-interacting)
IDBP-584246
syntabulin (syntaxin-interacting)
IDBP-588822
syntabulin (syntaxin-interacting)
IDBP-591229
syntabulin (syntaxin-interacting)
IDBP-590660
syntabulin (syntaxin-interacting)
IDBP-599870
syntabulin (syntaxin-interacting)
IDBP-588092
syntabulin (syntaxin-interacting)
IDBP-596325
syntabulin (syntaxin-interacting)
IDBP-598618
syntabulin (syntaxin-interacting)
IDBP-590134
syntabulin (syntaxin-interacting)
IDBP-596223
syntabulin (syntaxin-interacting)
IDBP-599375
syntabulin (syntaxin-interacting)
IDBP-586646
syntabulin (syntaxin-interacting)
IDBP-600604
syntabulin (syntaxin-interacting)
IDBP-602418
syntabulin (syntaxin-interacting)
IDBP-601460
syntabulin (syntaxin-interacting)
IDBP-600938
syntabulin (syntaxin-interacting)
IDBP-583884
syntabulin (syntaxin-interacting)
IDBP-590419
syntabulin (syntaxin-interacting)
IDBP-598139
syntabulin (syntaxin-interacting)
IDBP-598500
syntabulin (syntaxin-interacting)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Syntabulin/GOLSYN is part of a kinesin motor-adaptor complex that is critical for the anterograde axonal transport of active zone components and contributes to activity-dependent presynaptic assembly during neuronal development (Cai et al., 2007 [PubMed 17611281]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:109573978-109691791
Strand Reverse strand
Band q23.2
Transcripts
ENST00000276646 ENSP00000276646
ENST00000399066 ENSP00000382019
ENST00000408908 ENSP00000386154
ENST00000408889 ENSP00000386196
ENST00000422135 ENSP00000407118
ENST00000446070 ENSP00000414748
ENST00000433638 ENSP00000403544
ENST00000424158 ENSP00000415654
ENST00000440310 ENSP00000404369
ENST00000533895 ENSP00000433446
ENST00000532779 ENSP00000436266
ENST00000528331 ENSP00000436041
ENST00000529175 ENSP00000434871
ENST00000528647 ENSP00000432501
ENST00000533065 ENSP00000432962
ENST00000529690 ENSP00000433941
ENST00000533171 ENSP00000434679
ENST00000527707
ENST00000533394 ENSP00000431492
ENST00000532594 ENSP00000436850
ENST00000528045 ENSP00000436797
ENST00000527664
ENST00000528735
ENST00000529190 ENSP00000432835
ENST00000528569 ENSP00000434074
ENST00000532189 ENSP00000436908
ENST00000526736
ENST00000533821 ENSP00000431469
ENST00000530841 ENSP00000435433
ENST00000531230 ENSP00000434158
ENST00000534501 ENSP00000434840
ENST00000531284
ENST00000524720 ENSP00000435224
ENST00000534184 ENSP00000432291
ENST00000528716 ENSP00000436520
ENST00000526302 ENSP00000434061
ENST00000534578 ENSP00000431895
ENST00000527600 ENSP00000434612
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0017075 syntaxin-1 binding
GO:0019894 kinesin binding
Biological Process
GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus
Cellular Component
GO:0000139 Golgi membrane
GO:0005856 cytoskeleton
GO:0016021 integral component of membrane
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0097433 dense body
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022340
View Gene Order
ENSBTAG00000032548
Not yet available
Cross-References
SwissProt Q9NX95
TrEMBL B3KRD1 E9PI48 E9PJ11 E9PK96 E9PL50 E9PLB9 E9PN31 E9PPC2 E9PPS4 E9PQG2 E9PRT7
UniProt Splice Variant
Entrez Gene 55638
UniGene Hs.390738
RefSeq NM_001099744 NM_001099743 NM_001099745 NM_001099746 NM_001099747 NM_001099748 NM_001099749 NM_001099750 NM_001099751 NM_001099752 NM_001099753 NM_001099754 NM_001099755 NM_001099756 NM_017786 XM_005250999 XM_005251000 XM_006716600 XM_006716601
HUGO HGNC:26011
OMIM 611568
CCDS CCDS47912 CCDS43763 CCDS43764 CCDS55271
HPRD 07902
IMGT
EMBL AB040905 AB195676 AB195677 AB195678 AB195679 AC079061 AK000373 AK090559 AK091374 AK096558 AK290469 AL713645 AL834406 AY705385 BC012082 CH471060
GenPept AAH12082 AAU93914 BAA91121 BAA95996 BAD72976 BAD72977 BAD72978 BAD72979 BAF83158 BAG52185 BAG52343 BAG53323 CAD28457 CAD39068 EAW91937
RNA Seq Atlas 55638

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca