Version 5.4
Homo sapiens Gene: ASF1B
Summary
InnateDB Gene IDBG-32975.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ASF1B
Gene Name ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000105011
Encoded Proteins
IDBP-32977
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
IDBP-762014
IDBP-760026
IDBP-761100
IDBP-763265
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:14119509-14136956
Strand Reverse strand
Band p13.12
Transcripts
ENST00000263382 ENSP00000263382
ENST00000474890 ENSP00000466257
ENST00000592798 ENSP00000468513
ENST00000590835 ENSP00000464802
ENST00000589468 ENSP00000466409
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 58 experimentally validated interaction(s) in this database.
Experimentally validated
Total 58 [view]
Protein-Protein 55 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042393 histone binding
Biological Process
GO:0006333 chromatin assembly or disassembly
GO:0006334 nucleosome assembly
GO:0006335 DNA replication-dependent nucleosome assembly
GO:0006336 DNA replication-independent nucleosome assembly
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0016568 chromatin modification
GO:0030154 cell differentiation
Cellular Component
GO:0000785 chromatin
GO:0000790 nuclear chromatin
GO:0005634 nucleus
GO:0043234 protein complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000005470
View Gene Order
ENSBTAG00000004085
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_018154
HUGO
OMIM
CCDS CCDS12306
HPRD 16460
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca