Version 5.4
Homo sapiens Gene: PLEKHA7
Summary
InnateDB Gene IDBG-33615.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLEKHA7
Gene Name pleckstrin homology domain containing, family A member 7
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000166689
Encoded Proteins
IDBP-33617
pleckstrin homology domain containing, family A member 7
IDBP-602348
pleckstrin homology domain containing, family A member 7
IDBP-602565
pleckstrin homology domain containing, family A member 7
IDBP-599075
pleckstrin homology domain containing, family A member 7
IDBP-601288
pleckstrin homology domain containing, family A member 7
IDBP-585986
pleckstrin homology domain containing, family A member 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:16778295-17014443
Strand Reverse strand
Band p15.1
Transcripts
ENST00000355661 ENSP00000347883
ENST00000332954
ENST00000531066 ENSP00000435389
ENST00000529049
ENST00000533901
ENST00000531776
ENST00000530489 ENSP00000433467
ENST00000525781
ENST00000532079 ENSP00000434812
ENST00000533251
ENST00000525177
ENST00000525581 ENSP00000431455
ENST00000525049
ENST00000531079
ENST00000528376 ENSP00000435806
ENST00000528637
ENST00000529213
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0070097 delta-catenin binding
Biological Process
GO:0045218 zonula adherens maintenance
GO:0090136 epithelial cell-cell adhesion
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005915 zonula adherens
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000045659
View Gene Order
ENSBTAG00000006974
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
ecadherin_stabilization_pathway
Stabilization and expansion of the E-cadherin adherens junction
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.12332 Hs.603471 Hs.739092
RefSeq NM_175058 XM_005252802 XM_006718153
HUGO
OMIM
CCDS CCDS31434
HPRD 15142
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca