InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: ARIH2

Summary

InnateDB Gene

IDBG-33854.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ARIH2

Gene Name

ariadne homolog 2 (Drosophila)

Synonyms

ARI2; TRIAD1

Species

Homo sapiens

Ensembl Gene

ENSG00000177479

Encoded Proteins

IDBP-33856

ariadne homolog 2 (Drosophila)

IDBP-376588

ariadne homolog 2 (Drosophila)

IDBP-376590

ariadne homolog 2 (Drosophila)

IDBP-376614

ariadne homolog 2 (Drosophila)

IDBP-376623

ariadne homolog 2 (Drosophila)

IDBP-376626

ariadne homolog 2 (Drosophila)

IDBP-376628

ariadne homolog 2 (Drosophila)

IDBP-376632

ariadne homolog 2 (Drosophila)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:48918821-48986382

Strand

Forward strand

Band

p21.31

Transcripts

ENST00000356401	ENSP00000348769
ENST00000430423	ENSP00000399788
ENST00000452882	ENSP00000395560
ENST00000449376	ENSP00000403222
ENST00000420814	ENSP00000397225
ENST00000449729	ENSP00000404838
ENST00000433170	ENSP00000406063
ENST00000452385	ENSP00000403845
ENST00000478224
ENST00000498314
ENST00000474618
ENST00000492077
ENST00000463738
ENST00000490095
ENST00000495761
ENST00000482427
ENST00000483333
ENST00000488963
ENST00000486316
ENST00000474936
ENST00000466850
ENST00000470296
ENST00000484999
ENST00000463204
ENST00000495507
ENST00000472640
ENST00000459976
ENST00000465217
ENST00000482342
ENST00000469038
ENST00000487891

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 70 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	70 [view]
Protein-Protein	70 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0016874	ligase activity

Biological Process

GO:0000209	protein polyubiquitination
GO:0006511	ubiquitin-dependent protein catabolic process
GO:0007275	multicellular organismal development
GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0048588	developmental cell growth
GO:0070534	protein K63-linked ubiquitination
GO:0070936	protein K48-linked ubiquitination
GO:0071425	hematopoietic stem cell proliferation

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Orthologs

Species

Mus musculus

Bos taurus

Gene ID

Gene Order

ENSMUSG00000064145

View Gene Order

ENSBTAG00000005488

Not yet available

Pathways

NETPATH

REACTOME

REACT_75842

Antigen processing: Ubiquitination & Proteasome degradation pathway

REACT_75774

Adaptive Immune System pathway

REACT_6900

Immune System pathway

REACT_75820

Class I MHC mediated antigen processing & presentation pathway

KEGG

INOH

PID NCI

Cross-References

SwissProt

O95376

TrEMBL

C9JAU2 C9JBC5 C9JCL4 C9JZ71 Q6IBL8

UniProt Splice Variant

Entrez Gene

10425

UniGene

Hs.633601 Hs.658157

RefSeq

NM_006321 XM_005264798 XM_006712928 XM_006712929

HUGO

HGNC:690

OMIM

605615

CCDS

CCDS2780

HPRD

09286

IMGT

EMBL

AC134028 AC137630 AF099149 AF183427 AJ130978 AK313434 BC000422 CH471055 CR456785

GenPept

AAC82469 AAG09696 AAH00422 BAG36225 CAA10276 CAG33066 EAW64930 EAW64932 EAW64933

RNA Seq Atlas

10425