Version 5.4
Homo sapiens Gene: SLC47A2
Summary
InnateDB Gene IDBG-34910.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC47A2
Gene Name solute carrier family 47, member 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000180638
Encoded Proteins
IDBP-34912
solute carrier family 47, member 2
IDBP-34914
solute carrier family 47, member 2
IDBP-372620
solute carrier family 47, member 2
IDBP-759522
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein belonging to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each other on chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:19678288-19718979
Strand Reverse strand
Band p11.2
Transcripts
ENST00000325411 ENSP00000326671
ENST00000350657 ENSP00000338084
ENST00000456947
ENST00000433844 ENSP00000391848
ENST00000463318
ENST00000467609
ENST00000467379
ENST00000483510
ENST00000574239 ENSP00000458694
ENST00000574220
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0015238 drug transmembrane transporter activity
GO:0015297 antiporter activity
Biological Process
GO:0006855 drug transmembrane transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_19305
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.126830
RefSeq NM_001099646 NM_001256663 NM_152908 XM_006721454
HUGO
OMIM
CCDS CCDS11211 CCDS58530
HPRD 08710
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca