Version 5.4
Homo sapiens Gene: PTPN5
Summary
InnateDB Gene IDBG-35332.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PTPN5
Gene Name protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000110786
Encoded Proteins
IDBP-35334
protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
IDBP-238052
protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
IDBP-238054
protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
IDBP-238058
protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
IDBP-598953
protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:18727928-18792721
Strand Reverse strand
Band p15.1
Transcripts
ENST00000358540 ENSP00000351342
ENST00000396170 ENSP00000379473
ENST00000396168 ENSP00000379471
ENST00000396166 ENSP00000379469
ENST00000477854 ENSP00000435056
ENST00000496201
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001784 phosphotyrosine binding
GO:0004725 protein tyrosine phosphatase activity
GO:0016791 phosphatase activity
Biological Process
GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation
GO:0035335 peptidyl-tyrosine dephosphorylation
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030854
View Gene Order
ENSBTAG00000020257
Not yet available
Pathways
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
hsa04010
MAPK signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.79092
RefSeq NM_001039970 NM_001278236 NM_001278238 NM_001278239 NM_006906 NM_032781
HUGO
OMIM
CCDS CCDS41626 CCDS60746 CCDS7845
HPRD 01472
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca