Version 5.4
Mus musculus Gene: Ptpn5
Summary
InnateDB Gene IDBG-187284.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ptpn5
Gene Name protein tyrosine phosphatase, non-receptor type 5
Synonyms Step
Species Mus musculus
Ensembl Gene ENSMUSG00000030854
Encoded Proteins
IDBP-187288
protein tyrosine phosphatase, non-receptor type 5
IDBP-187290
protein tyrosine phosphatase, non-receptor type 5
IDBP-266284
protein tyrosine phosphatase, non-receptor type 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000110786:
Gene Information
Type Protein coding
Genomic Location Chromosome 7:47077798-47133684
Strand Reverse strand
Band B3
Transcripts
ENSMUST00000102626 ENSMUSP00000099686
ENSMUST00000033142 ENSMUSP00000033142
ENSMUST00000107617 ENSMUSP00000103242
ENSMUST00000126370
ENSMUST00000153192
ENSMUST00000128358
ENSMUST00000139057
ENSMUST00000149785
ENSMUST00000137722
ENSMUST00000145321
ENSMUST00000130381
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001784 phosphotyrosine binding
GO:0004725 protein tyrosine phosphatase activity
GO:0016791 phosphatase activity
Biological Process
GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation
GO:0035335 peptidyl-tyrosine dephosphorylation
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000110786
View Gene Order
ENSBTAG00000020257
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04010
MAPK signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
hsa04010
MAPK signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt P54830
TrEMBL
UniProt Splice Variant
Entrez Gene 19259
UniGene Mm.420139 Mm.4654
RefSeq NM_001163565 NM_013643 XM_006540713 XM_006540714 XM_006540716
OMIM
CCDS CCDS21294
HPRD
IMGT
MGI ID MGI:97807
MGI Symbol Ptpn5
EMBL AK038416 BC079592 CH466603 S80329 U28216 U28217
GenPept AAA73573 AAA73574 AAB35656 AAH79592 BAC29993 EDL22958
RNA Seq Atlas 19259

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca