Version 5.4
Homo sapiens Gene: SLCO4C1
Summary
InnateDB Gene IDBG-35380.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLCO4C1
Gene Name solute carrier organic anion transporter family, member 4C1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000173930
Encoded Proteins
IDBP-35382
solute carrier organic anion transporter family, member 4C1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary SLCO4C1 belongs to the organic anion transporter (OATP) family. OATPs are involved in the membrane transport of bile acids, conjugated steroids, thyroid hormone, eicosanoids, peptides, and numerous drugs in many tissues (Mikkaichi et al., 2004 [PubMed 14993604]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:102233986-102296549
Strand Reverse strand
Band q21.1
Transcripts
ENST00000310954 ENSP00000309741
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0030154 cell differentiation
GO:0043252 sodium-independent organic anion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000040693
View Gene Order
ENSBTAG00000016359
Not yet available
Pathways
NETPATH
REACTOME
REACT_23988
Transport of organic anions pathway
REACT_22285
Transport of vitamins, nucleosides, and related molecules pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q6ZQN7
TrEMBL Q63HP3
UniProt Splice Variant
Entrez Gene 353189
UniGene Hs.127648
RefSeq NM_180991
HUGO HGNC:23612
OMIM 609013
CCDS CCDS34205
HPRD
IMGT
EMBL AF401643 AK128854 AY273896 BX647880 CH471086
GenPept AAP33047 AAQ03086 BAC87647 CAH56201 EAW49099
RNA Seq Atlas 353189

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca