Version 5.4
Homo sapiens Gene: POLI
Summary
InnateDB Gene IDBG-3542.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POLI
Gene Name polymerase (DNA directed) iota
Synonyms RAD30B; RAD3OB
Species Homo sapiens
Ensembl Gene ENSG00000101751
Encoded Proteins
IDBP-3544
polymerase (DNA directed) iota
IDBP-294642
polymerase (DNA directed) iota
IDBP-725742
IDBP-725837
IDBP-728179
IDBP-727846
IDBP-726107
IDBP-727323
IDBP-726516
IDBP-726373
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 18:54269404-54321266
Strand Forward strand
Band q21.2
Transcripts
ENST00000217800 ENSP00000217800
ENST00000406285 ENSP00000385196
ENST00000579434 ENSP00000462681
ENST00000577612 ENSP00000464025
ENST00000583136 ENSP00000463071
ENST00000580905
ENST00000582366
ENST00000579823 ENSP00000463065
ENST00000580880 ENSP00000461983
ENST00000577727
ENST00000579534 ENSP00000462664
ENST00000577971
ENST00000583576
ENST00000585023 ENSP00000463971
ENST00000581950 ENSP00000462146
ENST00000577361
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 22 [view]
Protein-Protein 21 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006261 DNA-dependent DNA replication
GO:0006281 DNA repair
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038425
View Gene Order
ENSBTAG00000009129
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.128076 Hs.438533 Hs.608280
RefSeq NM_007195 XM_005258188 XM_005258191 XM_005258192 XM_006722376 XM_006722377
HUGO
OMIM
CCDS CCDS11954
HPRD 16094
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca