Version 5.4
Homo sapiens Gene: PDP2
Summary
InnateDB Gene IDBG-35686.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDP2
Gene Name pyruvate dehyrogenase phosphatase catalytic subunit 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000172840
Encoded Proteins
IDBP-35688
pyruvate dehyrogenase phosphatase catalytic subunit 2
IDBP-749472
IDBP-752866
IDBP-745777
IDBP-750299
IDBP-746492
IDBP-753886
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 16:66878589-66895754
Strand Forward strand
Band q22.1
Transcripts
ENST00000311765 ENSP00000309548
ENST00000568869 ENSP00000456611
ENST00000566776 ENSP00000455975
ENST00000566543 ENSP00000457331
ENST00000568720
ENST00000561704 ENSP00000457951
ENST00000566805 ENSP00000457675
ENST00000568398 ENSP00000456171
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004722 protein serine/threonine phosphatase activity
GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity
GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0006090 pyruvate metabolic process
GO:0006470 protein dephosphorylation
GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate
GO:0035970 peptidyl-threonine dephosphorylation
GO:0044237 cellular metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000048371
View Gene Order
ENSBTAG00000046708
Not yet available
Pathways
NETPATH
REACTOME
REACT_12528
Regulation of pyruvate dehydrogenase (PDH) complex pathway
REACT_2071
Pyruvate metabolism pathway
REACT_1046
Pyruvate metabolism and Citric Acid (TCA) cycle pathway
REACT_111083
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_111217
Metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.632214 Hs.742034
RefSeq NM_020786 XM_005256064 XM_005256065 XM_005256066 XM_005256067 XM_005256068
HUGO
OMIM
CCDS CCDS10822
HPRD 15112
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca