Version 5.4
Homo sapiens Gene: PJA2
Summary
InnateDB Gene IDBG-36293.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PJA2
Gene Name praja ring finger 2, E3 ubiquitin protein ligase
Synonyms Neurodap1; RNF131
Species Homo sapiens
Ensembl Gene ENSG00000198961
Encoded Proteins
IDBP-36295
praja ring finger 2
IDBP-36297
praja ring finger 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:109334709-109409994
Strand Reverse strand
Band q21.3
Transcripts
ENST00000361189 ENSP00000354775
ENST00000361557 ENSP00000355284
ENST00000511624
ENST00000512822
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 26 [view]
Protein-Protein 25 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0034236 protein kinase A catalytic subunit binding
GO:0034237 protein kinase A regulatory subunit binding
GO:0046872 metal ion binding
Biological Process
GO:0007616 long-term memory
GO:0010738 regulation of protein kinase A signaling
GO:0016567 protein ubiquitination
Cellular Component
GO:0000139 Golgi membrane
GO:0005737 cytoplasm
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0014069 postsynaptic density
GO:0030054 cell junction
GO:0045211 postsynaptic membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024083
View Gene Order
ENSBTAG00000021675
Not yet available
Pathways
NETPATH
REACTOME
REACT_75842
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt O43164
TrEMBL
UniProt Splice Variant
Entrez Gene 9867
UniGene Hs.483036
RefSeq NM_014819
HUGO HGNC:17481
OMIM
CCDS CCDS4099
HPRD
IMGT
EMBL AB007898 AC008467 AC010625 AK291759 BC030826 CH471086 CR749579
GenPept AAH30826 BAA23710 BAF84448 CAH18371 EAW49050 EAW49051
RNA Seq Atlas 9867

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca