Version 5.4
Homo sapiens Gene: PGLS
Summary
InnateDB Gene IDBG-36778.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PGLS
Gene Name 6-phosphogluconolactonase
Synonyms 6PGL
Species Homo sapiens
Ensembl Gene ENSG00000130313
Encoded Proteins
IDBP-36780
6-phosphogluconolactonase
IDBP-765938
IDBP-762168
IDBP-761113
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:17511629-17521288
Strand Forward strand
Band p13.11
Transcripts
ENST00000252603 ENSP00000252603
ENST00000595782 ENSP00000471951
ENST00000594761 ENSP00000471446
ENST00000600923 ENSP00000472345
ENST00000598811
ENST00000596799
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0017057 6-phosphogluconolactonase activity
GO:0048029 monosaccharide binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006098 pentose-phosphate shunt
GO:0009051 pentose-phosphate shunt, oxidative branch
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031807
View Gene Order
ENSBTAG00000016783
Not yet available
Pathways
NETPATH
REACTOME
REACT_1859
Pentose phosphate pathway (hexose monophosphate shunt) pathway
REACT_200783
Myoclonic epilepsy of Lafora pathway
REACT_474
Metabolism of carbohydrates pathway
REACT_111217
Metabolism pathway
REACT_116125
Disease pathway
REACT_200833
Glycogen storage diseases pathway
KEGG
hsa00030
Pentose phosphate pathway pathway
INOH
INOH website
Pentose phosphate cycle pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_012088
HUGO
OMIM
CCDS CCDS12361
HPRD 12001
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca