Version 5.4
Homo sapiens Gene: PCDH9
Summary
InnateDB Gene IDBG-36883.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PCDH9
Gene Name protocadherin 9
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000184226
Encoded Proteins
IDBP-36885
protocadherin 9
IDBP-36891
protocadherin 9
IDBP-370137
protocadherin 9
IDBP-598318
protocadherin 9
IDBP-811000
protocadherin 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the protocadherin family, and cadherin superfamily, of transmembrane proteins containing cadherin domains. These proteins mediate cell adhesion in neural tissues in the presence of calcium. The encoded protein may be involved in signaling at neuronal synaptic junctions. Sharing a characteristic with other protocadherin genes, this gene has a notably large exon that encodes multiple cadherin domains and a transmembrane region. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Nov 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:66302834-67230445
Strand Reverse strand
Band q21.32
Transcripts
ENST00000377865 ENSP00000367096
ENST00000377861 ENSP00000367092
ENST00000456367 ENSP00000401699
ENST00000544246 ENSP00000442186
ENST00000617020
ENST00000614931 ENSP00000482917
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0007156 homophilic cell adhesion
GO:0030900 forebrain development
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030426 growth cone
GO:0044291 cell-cell contact zone
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000055421
View Gene Order
ENSBTAG00000019340
Not yet available
Cross-References
SwissProt Q9HC56
TrEMBL B7ZM79 Q5VT82 X5D7N0
UniProt Splice Variant
Entrez Gene 5101
UniGene Hs.601596 Hs.615839 Hs.654709
RefSeq NM_020403 NM_203487 XM_005266406
HUGO HGNC:8661
OMIM 603581
CCDS CCDS9443 CCDS9444
HPRD
IMGT
EMBL AF169692 AL136999 AL138682 AL138814 AL160254 AL355173 AL356305 AL450107 AL603863 AL834258 BC136626 BC136627 BC144321 BX537422 CH471093 KJ534915
GenPept AAF89689 AAI36627 AAI36628 AAI44322 AHW56555 CAD38933 CAD97664 CAH72612 CAH72759 CAI12502 CAM13066 CAM13771 CAM17290 CAM17491 EAW80499
RNA Seq Atlas 5101

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca