Version 5.4
Homo sapiens Gene: KCNK9
Summary
InnateDB Gene IDBG-36932.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNK9
Gene Name potassium channel, subfamily K, member 9
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000169427
Encoded Proteins
IDBP-36934
potassium channel, subfamily K, member 9
IDBP-482991
potassium channel, subfamily K, member 9
IDBP-476408
potassium channel, subfamily K, member 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains, and is highly expressed in the cerebellum. Amplification and overexpression of this gene has been observed in several types of human carcinomas, notably in breast cancer. This gene is imprinted in fetal brain, with preferential expression from the maternal allele. [provided by RefSeq, Oct 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:139600838-139703056
Strand Reverse strand
Band q24.3
Transcripts
ENST00000303015 ENSP00000302166
ENST00000522317 ENSP00000429847
ENST00000523477
ENST00000523653
ENST00000519923
ENST00000520439 ENSP00000430676
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005244 voltage-gated ion channel activity
GO:0005267 potassium channel activity
GO:0042803 protein homodimerization activity
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006813 potassium ion transport
GO:0007268 synaptic transmission
GO:0034765 regulation of ion transmembrane transport
GO:0071805 potassium ion transmembrane transport
GO:0090102 cochlea development
Cellular Component
GO:0005886 plasma membrane
GO:0008021 synaptic vesicle
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036760
View Gene Order
ENSBTAG00000047488
Not yet available
Pathways
NETPATH
REACTOME
REACT_75899
TWIK-releated acid-sensitive K+ channel (TASK) pathway
REACT_75897
Tandem pore domain potassium channels pathway
REACT_13685
Neuronal System pathway
REACT_75908
Potassium Channels pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.493037
RefSeq NM_001282534
HUGO
OMIM
CCDS CCDS6377
HPRD 16167
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca