Version 5.4
| Homo sapiens Gene: DNAJC24 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-37306.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | DNAJC24 | ||||||||
| Gene Name | DnaJ (Hsp40) homolog, subfamily C, member 24 | ||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Gene | ENSG00000170946 | ||||||||
| Encoded Proteins |
DnaJ (Hsp40) homolog, subfamily C, member 24
DnaJ (Hsp40) homolog, subfamily C, member 24
DnaJ (Hsp40) homolog, subfamily C, member 24
DnaJ (Hsp40) homolog, subfamily C, member 24
DnaJ (Hsp40) homolog, subfamily C, member 24
DnaJ (Hsp40) homolog, subfamily C, member 24
DnaJ (Hsp40) homolog, subfamily C, member 24
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM, Mar 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 11:31369840-31432832 | ||||||||
| Strand | Forward strand | ||||||||
| Band | p13 | ||||||||
| Transcripts | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | |||||||||
| UniGene | Hs.187269 Hs.613612 | ||||||||
| RefSeq | NM_181706 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | CCDS7873 | ||||||||
| HPRD | 15705 | ||||||||
| IMGT | |||||||||
| EMBL | |||||||||
| GenPept | |||||||||
| RNA Seq Atlas | |||||||||