Version 5.4
Homo sapiens Gene: MYO18A
Summary
InnateDB Gene IDBG-38066.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MYO18A
Gene Name myosin XVIIIA
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000196535
Encoded Proteins
IDBP-587679
myosin XVIIIA
IDBP-586556
myosin XVIIIA
IDBP-587609
myosin XVIIIA
IDBP-594692
myosin XVIIIA
IDBP-596456
myosin XVIIIA
IDBP-764154
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 25965346
[Mus musculus] Myo18a isoforms differentially regulate trafficking, expression, and activation of innate immune receptors on macrophages
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:29073517-29180412
Strand Reverse strand
Band q11.2
Transcripts
ENST00000529578
ENST00000533112 ENSP00000435932
ENST00000531253 ENSP00000434228
ENST00000527372 ENSP00000437073
ENST00000530254 ENSP00000434817
ENST00000532867
ENST00000527312
ENST00000531438
ENST00000531892
ENST00000529889
ENST00000530557
ENST00000533652
ENST00000532143
ENST00000533399
ENST00000528564 ENSP00000436660
ENST00000528322
ENST00000531267
ENST00000533420
ENST00000546105
ENST00000590565
ENST00000585573
ENST00000588791 ENSP00000465542
ENST00000590242
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003774 motor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008094 DNA-dependent ATPase activity
GO:0043531 ADP binding
GO:0044822 poly(A) RNA binding
GO:0051015 actin filament binding
Biological Process
GO:0006259 DNA metabolic process
GO:0007030 Golgi organization
GO:0016477 cell migration
GO:0031032 actomyosin structure organization
GO:0038032 termination of G-protein coupled receptor signaling pathway
GO:0043066 negative regulation of apoptotic process
GO:0048194 Golgi vesicle budding
GO:0050714 positive regulation of protein secretion
Cellular Component
GO:0000139 Golgi membrane
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005802 trans-Golgi network
GO:0005856 cytoskeleton
GO:0016020 membrane
GO:0016459 myosin complex
GO:0042641 actomyosin
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000000631
View Gene Order
ENSBTAG00000017380
Not yet available
Pathways
NETPATH
REACTOME
REACT_121141
Signaling by FGFR1 fusion mutants pathway
REACT_121398
Signaling by FGFR mutants pathway
REACT_120736
Signaling by FGFR in disease pathway
REACT_120999
Signaling by FGFR1 mutants pathway
REACT_116125
Disease pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.462590
RefSeq NM_078471 NM_203318
HUGO
OMIM
CCDS CCDS45641 CCDS45642
HPRD 10106
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca