Version 5.4
Mus musculus Gene: Myo18a
Summary
InnateDB Gene IDBG-201810.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Myo18a
Gene Name myosin XVIIIA
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000000631
Encoded Proteins
IDBP-201812
myosin XVIIIA
IDBP-201814
myosin XVIIIA
IDBP-201816
myosin XVIIIA
IDBP-201822
myosin XVIIIA
IDBP-201826
myosin XVIIIA
IDBP-264647
myosin XVIIIA
IDBP-264649
myosin XVIIIA
IDBP-539491
myosin XVIIIA
IDBP-534229
myosin XVIIIA
IDBP-537302
myosin XVIIIA
IDBP-532971
myosin XVIIIA
IDBP-622639
myosin XVIIIA
IDBP-622640
myosin XVIIIA
IDBP-622641
myosin XVIIIA
IDBP-622645
myosin XVIIIA
IDBP-622647
myosin XVIIIA
IDBP-622650
myosin XVIIIA
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 25965346
Myo18a isoforms differentially regulate trafficking, expression, and activation of innate immune receptors on macrophages
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196535:
Gene Information
Type Protein coding
Genomic Location Chromosome 11:77763246-77865980
Strand Forward strand
Band B5
Transcripts
ENSMUST00000100443
ENSMUST00000102488 ENSMUSP00000099546
ENSMUST00000000645 ENSMUSP00000000645
ENSMUST00000092887 ENSMUSP00000090563
ENSMUST00000100795
ENSMUST00000100794 ENSMUSP00000098358
ENSMUST00000092884 ENSMUSP00000090560
ENSMUST00000108376 ENSMUSP00000104013
ENSMUST00000108375 ENSMUSP00000104012
ENSMUST00000130627 ENSMUSP00000119839
ENSMUST00000130305 ENSMUSP00000119574
ENSMUST00000151373 ENSMUSP00000123256
ENSMUST00000154892
ENSMUST00000134196
ENSMUST00000135045
ENSMUST00000130956
ENSMUST00000135375 ENSMUSP00000117044
ENSMUST00000142571
ENSMUST00000133740
ENSMUST00000164315 ENSMUSP00000129084
ENSMUST00000168348 ENSMUSP00000130696
ENSMUST00000169105 ENSMUSP00000132149
ENSMUST00000172303 ENSMUSP00000129098
ENSMUST00000164334 ENSMUSP00000131771
ENSMUST00000167856 ENSMUSP00000128487
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003774 motor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0043531 ADP binding
GO:0044822 poly(A) RNA binding
GO:0051015 actin filament binding
Biological Process
GO:0007030 Golgi organization
GO:0008152 metabolic process
GO:0016477 cell migration
GO:0031032 actomyosin structure organization
GO:0038032 termination of G-protein coupled receptor signaling pathway
GO:0045087 innate immune response (InnateDB)
GO:0048194 Golgi vesicle budding
GO:0050714 positive regulation of protein secretion
Cellular Component
GO:0000139 Golgi membrane
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005802 trans-Golgi network
GO:0005856 cytoskeleton
GO:0016020 membrane
GO:0016459 myosin complex
GO:0042641 actomyosin
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000196535
View Gene Order
ENSBTAG00000017380
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_121141
Signaling by FGFR1 fusion mutants pathway
REACT_121398
Signaling by FGFR mutants pathway
REACT_120736
Signaling by FGFR in disease pathway
REACT_120999
Signaling by FGFR1 mutants pathway
REACT_116125
Disease pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.341248 Mm.398155 Mm.438968 Mm.472287 Mm.476162
RefSeq NM_001291212 NM_001291213 NM_001291214 NM_001291215 NM_011586 XM_006533594 XM_006533599 XM_006533603 XM_006533604 XM_006533605 XM_006533606 XM_006533612 XM_006533613 XM_006533614
OMIM
CCDS CCDS25085 CCDS70252 CCDS70253
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca