Version 5.4
Homo sapiens Gene: ELF2
Summary
InnateDB Gene IDBG-38206.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ELF2
Gene Name E74-like factor 2 (ets domain transcription factor)
Synonyms EU32; NERF; NERF-1A; NERF-1a,b; NERF-1B; NERF-2
Species Homo sapiens
Ensembl Gene ENSG00000109381
Encoded Proteins
IDBP-38208
E74-like factor 2 (ets domain transcription factor)
IDBP-38212
E74-like factor 2 (ets domain transcription factor)
IDBP-38214
E74-like factor 2 (ets domain transcription factor)
IDBP-242009
E74-like factor 2 (ets domain transcription factor)
IDBP-377790
E74-like factor 2 (ets domain transcription factor)
IDBP-480733
E74-like factor 2 (ets domain transcription factor)
IDBP-483645
E74-like factor 2 (ets domain transcription factor)
IDBP-481200
E74-like factor 2 (ets domain transcription factor)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:139028112-139177218
Strand Reverse strand
Band q31.1
Transcripts
ENST00000379550 ENSP00000368868
ENST00000358635 ENSP00000351458
ENST00000379549 ENSP00000368867
ENST00000394235 ENSP00000377782
ENST00000420916 ENSP00000397796
ENST00000515489
ENST00000510408 ENSP00000426997
ENST00000512627 ENSP00000426087
ENST00000514577
ENST00000504314
ENST00000514606
ENST00000511184 ENSP00000421278
ENST00000511006
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 7 [view]
Protein-DNA 2 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0030154 cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037174
View Gene Order
ENSBTAG00000020594
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
angiopoietinreceptor_pathway
Angiopoietin receptor Tie2-mediated signaling
Cross-References
SwissProt Q15723
TrEMBL
UniProt Splice Variant
Entrez Gene 1998
UniGene Hs.634040 Hs.656593
RefSeq XM_005262803 XM_006714130 NM_001276457 NM_001276458 NM_001276459 NM_006874 NM_201999 XM_005262804 XM_005262806 XM_006714129
HUGO HGNC:3317
OMIM
CCDS CCDS3744 CCDS3745 CCDS64062 CCDS64063
HPRD 16856
IMGT
EMBL AC024032 AC093602 AF256222 AF256223 BC034951 BC065025 U43188 U43189
GenPept AAB37759 AAB37760 AAB37761 AAF67195 AAF67196 AAH34951 AAH65025
RNA Seq Atlas 1998

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca